The most common reason for menopause is the natural decline in a female's reproductive hormones. However, menopause can also result from the following situations:
Oophorectomy: This surgery, which removes a woman's ovaries, causes immediate menopause. Symptoms and signs of menopause in this situation can be severe, as the hormonal changes happen abruptly.
Chemotherapy: Cancer treatments like chemotherapy can induce menopause quickly, causing symptoms to appear shortly after or even during treatment.
Ovarian Insufficiency: Also called premature ovarian failure, this condition is essentially premature menopause. It happens when a woman's ovaries quit functioning before the age of 40 and can stem from genetic factors and disease. Only 1% of women suffer from premature menopause, but HRT can help protect the heart, brain, and bones.
If you're a woman going through menopause and find that you have become increasingly depressed, you're not alone. It's estimated that 15% of women experience depression to some degree while going through menopause. What many women don't know is that depression can start during perimenopause, or the years leading up to menopause.
Depression can be hard to diagnose, especially during perimenopause and menopause. However, if you notice the following signs, it might be time to speak with a physician:
Remember, if you're experiencing depression, you're not weak or broken - you're going through a very regular emotional experience. The good news is that with proper treatment from your doctor, depression isn't a death sentence. And with HRT and anti-aging treatment for women, depression could be the catalyst you need to enjoy a new lease on life.
Hot flashes - they're one of the most well-known symptoms of menopause. Hot flashes are intense, sudden feelings of heat across a woman's upper body. Some last second, while others last minutes, making them incredibly inconvenient and uncomfortable for most women.
Symptoms of hot flashes include:
Typically, hot flashes are caused by a lack of estrogen. Low estrogen levels negatively affect a woman's hypothalamus, the part of the brain that controls body temperature and appetite. Low estrogen levels cause the hypothalamus to incorrectly assume the body is too hot, dilating blood vessels to increase blood flow. Luckily, most women don't have to settle for the uncomfortable feelings that hot flashes cause. HRT treatments for women often stabilize hormones, lessening the effects of hot flashes and menopause in general.
Mood swings are common occurrences for most people - quick shifts from happy to angry and back again, triggered by a specific event. And while many people experience mood swings, they are particularly common for women going through menopause. That's because, during menopause, the female's hormones are often imbalanced. Hormone imbalances and mood swings go hand-in-hand, resulting in frequent mood changes and even symptoms like insomnia.
The rate of production of estrogen, a hormone that fluctuates during menopause, largely determines the rate of production the hormone serotonin, which regulates mood, causing mood swings.
Luckily, HRT and anti-aging treatments in Boonton, NJ for women work wonders for mood swings by regulating hormone levels like estrogen. With normal hormone levels, women around the world are now learning that they don't have to settle for mood swings during menopause.
Staying fit and healthy is hard for anyone living in modern America. However, for women with hormone imbalances during perimenopause or menopause, weight gain is even more serious. Luckily, HRT treatments for women coupled with a physician-led diet can help keep weight in check. But which hormones need to be regulated?
Lowered sexual desire - three words most men and women hate to hear. Unfortunately, for many women in perimenopausal and menopausal states, it's just a reality of life. Thankfully, today, HRT and anti-aging treatments Boonton, NJ can help women maintain a normal, healthy sex drive. But what causes low libido in women, especially as they get older?
The hormones responsible for low libido in women are progesterone, estrogen, and testosterone.
Progesterone production decreases during perimenopause, causing low sex drive in women. Lower progesterone production can also cause chronic fatigue, weight gain, and other symptoms. On the other hand, lower estrogen levels during menopause lead to vaginal dryness and even vaginal atrophy or loss of muscle tension.
Lastly, testosterone plays a role in lowered libido. And while testosterone is often grouped as a male hormone, it contributes to important health and regulatory functionality in women. A woman's testosterone serves to heighten sexual responses and enhances orgasms. When the ovaries are unable to produce sufficient levels of testosterone, it often results in a lowered sex drive.
Often uncomfortable and even painful, vaginal dryness is a serious problem for sexually active women. However, like hair loss in males, vaginal dryness is very common - almost 50% of women suffer from it during menopause.
Getting older is just a part of life, but that doesn't mean you have to settle for the side effects. HRT and anti-aging treatments for women correct vaginal dryness by re-balancing estrogen, progesterone, and testosterone. When supplemented with diet and healthy living, your vagina's secretions are normalized, causing discomfort to recede.
Uterine fibroids - they're perhaps the least-known symptom of menopause and hormone imbalances in women. That's because these growths on the uterus are often symptom-free. Unfortunately, these growths can be cancerous, presenting a danger for women as they age.
Many women will have fibroids at some point. Because they're symptomless, they're usually found during routine doctor exams. Some women only get one or two, while others may have large clusters of fibroids. Because fibroids are usually caused by hormone imbalances, hysterectomies have been used as a solution, forcing women into early menopause.
Advances in HRT and anti-aging medicine for women give females a safer, non-surgical option without having to experience menopause early. At Global Life Rejuvenation, our expert physicians will implement a customized HRT program to stabilize your hormones and reduce the risk of cancerous fibroid growth.
Endometriosis symptoms are much like the effects of PMS, and include pelvic pain, fatigue, cramping, and bloating. While doctors aren't entirely sure what causes this painful, uncomfortable condition, most agree that hormones - particularly xenoestrogens - play a factor.
Endometriosis symptoms are much like the effects of PMS and include pelvic pain, fatigue, cramping, and bloating. While doctors aren't entirely sure what causes this painful, uncomfortable condition, most agree that hormones - particularly xenoestrogens - play a factor.
Xenoestrogen is a hormone that is very similar to estrogen. Too much xenoestrogen is thought to stimulate endometrial tissue growth. HRT for women helps balance these hormones and, when used with a custom nutrition program, can provide relief for women across the U.S.
Sermorelin is a synthetic hormone peptide, like GHRH, which triggers the release of growth hormones. When used under the care of a qualified physician, Sermorelin can help you lose weight, increase your energy levels, and help you feel much younger.
Human growth hormone (HGH) therapy has been used for years to treat hormone deficiencies. Unlike HGH, which directly replaces declining human growth hormone levels, Sermorelin addresses the underlying cause of decreased HGH, stimulating the pituitary gland naturally. This approach keeps the mechanisms of growth hormone production active.
Ipamorelin helps to release growth hormones in a person's body by mimicking a peptide called ghrelin. Ghrelin is one of three hormones which work together to regulate the growth hormone levels released by the pituitary gland. Because Ipamorelin stimulates the body to produce growth hormone, your body won't stop its natural growth hormone production, which occurs with synthetic HGH.
Ipamorelin causes growth hormone secretion that resembles natural release patterns rather than being constantly elevated from HGH. Because ipamorelin stimulates the natural production of growth hormone, our patients can use this treatment long-term with fewer health risks.
One of the biggest benefits of Ipamorelin is that it provides significant short and long-term benefits in age management therapies. Ipamorelin can boost a patient's overall health, wellbeing, and outlook on life.
When growth hormone is produced by the pituitary gland using Ipamorelin, clients report amazing benefits. Some of those benefits include:
Whether you are considering our HRT and anti-aging treatments for women in Boonton, NJ, we are here to help. The first step to reclaiming your life begins by contacting Global Life Rejuvenation. Our friendly, knowledgeable HRT experts can help answer your questions and walk you through our procedures. From there, we'll figure out which treatments are right for you. Before you know it, you'll be well on your way to looking and feeling better than you have in years!973-587-8638
Article describes Enteris' strengths and scalability in working with highly potent active pharmaceutical ingredientsBOONTON, N.J., August 3, 2022 /PRNewswire/ -- Enteris BioPharma, Inc., a biotechnology company developing innovative drug products based on its proprietary delivery techno...
Article describes Enteris' strengths and scalability in working with highly potent active pharmaceutical ingredients
BOONTON, N.J., August 3, 2022 /PRNewswire/ -- Enteris BioPharma, Inc., a biotechnology company developing innovative drug products based on its proprietary delivery technologies, and a wholly-owned subsidiary of SWK Holdings Corporation (Nasdaq: SWKH), announced today that Director of Manufacturing at Enteris, Angelo P. Consalvo, was featured in Drug Development and Delivery discussing the capabilities of Enteris as a specialized CDMO able to overcome the pandemic-induced disruption of supply chains for highly potent active pharmaceutical ingredients (HPAPIs). The feature can be accessed at https://drug-dev.com/special-feature-outsourcing-formulation-development-manufacturing-understanding-critical-attributes-earlier-in-development-leads-to-a-more-robust-drug-product/#enteris
In the article, Mr. Consalvo discussed the skills necessary to work with HPAPIs, the need for quality and safety in manufacturing with these products, and how Enteris has the flexibility and expertise to provide solid oral dosages of these products for clinical trials and small-scale commercial production.
"We are honored to be included in the Drug Development & Delivery special feature and explain how Enteris is responding to a gap in the manufacture of HPAPI solid oral drugs," stated Mr. Consalvo. "The pandemic has tragically highlighted the fragility of larger CMOs. We are proud to offer our specialized skill set and meet a variety of manufacturing needs. We can overcome traditional challenges in the development of HPAPIs such as achieving content uniformity and bioavailability for low-dose, limited quantity products. Most importantly, we can manufacture our high-quality products while saving significant time and resources, prioritizing both safety and efficiency. We are excited to share our knowledge and welcome the opportunity to work with both large pharmaceutical companies and smaller biotechs to service their HPAPI needs."
Enteris BioPharma completed the renovation of its Boonton, NJ, manufacturing plant, which now encompasses a 32,000-square-foot, state-of-the-art facility with multiple suites dedicated to HPAPI handling/containment and solid oral dose manufacturing. This technical capacity is complemented by extensive experience and specialized knowledge working with HPAPIs and low-dose formulations to achieve excellent content uniformity.
About Enteris BioPharma
Enteris BioPharma, Inc. is a wholly-owned subsidiary of SWK Holdings Corporation (Nasdaq: SWKH) offering total integrated contract development and manufacturing (CDMO) services for innovative formulation solutions utilizing its proprietary drug delivery technologies, Peptelligence® and ProPerma®, and contract manufacturing (CMO) services using non-proprietary technologies. The company's proprietary technologies have been the subject of numerous feasibility studies and active development programs, some of which are in clinical development. Additionally, Enteris BioPharma is advancing an innovative internal product pipeline of drug products that address significant unmet clinical needs for which there is no satisfactory treatment option. For more information on Enteris BioPharma and its proprietary oral drug delivery technologies, please visit http://www.EnterisBioPharma.com.
View original content:https://www.prnewswire.com/news-releases/enteris-biopharma-manufacturing-expertise-highlighted-in-drug-development--delivery-special-feature-on-outsourcing-formulation-development--manufacturing-301598844.html
SOURCE Enteris BioPharma, Inc.
PRINT:BOONTON — Gov. Phil Murphy, Acting Education Commissioner Angelica Allen-McMillan and U.S. Rep. Mikie Sherrill touted the Murphy administration’s expanded investments in pre-kindergarten on Wednesday.The officials toured a preschool academy housed in Boonton High School visiting classrooms and taking part in some drawing activities with the students. Murphy later went to the Boonton Coffee Co. café for a roundtable discussion with four local pre-k mothers.According to the governo...
BOONTON — Gov. Phil Murphy, Acting Education Commissioner Angelica Allen-McMillan and U.S. Rep. Mikie Sherrill touted the Murphy administration’s expanded investments in pre-kindergarten on Wednesday.
The officials toured a preschool academy housed in Boonton High School visiting classrooms and taking part in some drawing activities with the students. Murphy later went to the Boonton Coffee Co. café for a roundtable discussion with four local pre-k mothers.
According to the governor’s office, Murphy’s FY2023 budget proposal includes an increase of $68 million in pre-K aid over last year, for a total of $991.8 million spent on pre-k. Boonton is set to receive over $1.8 million in preschool aid this year.
“Hello ladies and gentlemen” Murphy greeted the three and four-year-olds seated on a rug in the first classroom. Most of the children laughed. “That wasn’t intended to be a laugh line,” Murphy joked.
In the next classroom, some students asked the governor questions including: “how is the office?” and “can I be governor too?”
“Yeah, you want to do that today?” Murphy offered the boy, Christian, who had asked to take over the state leadership role.
Hearing the response, several other students asked if they too could be governor.
“You all can,” Murphy said.
One student told Murphy “I love you.”
Murphy responded “thank you for that man, love you right back…I only wish you could vote.”
The teacher told Christian she would give his phone number to Murphy’s people.
In the final classroom students practiced drawing shapes and naming things that were those shapes. Students said triangles could be pizza, a tent or watermelon. Squares could be windows, presents or a fish tank.
One kid, who had drawn on himself in black marker, told Murphy “your head is red.”
“Yeah it is I got sunburned,” Murphy said.
After the classroom visits, Murphy talked with the head of school who said the pre-k’s integration within the high school building has been good. Some high school students have siblings in the pre-k and the school has a program set up for the 12th graders to work with the younger kids and graduate with a Child Development Associate (CDA) Educational Certificate of Achievement.
At the coffeeshop after the school tour, Murphy talked with four mothers whose students are enrolled in the pre-k program.
They spoke about how the Covid-19 pandemic affected their children and how important being back in school in-person has been for their families.
Murphy said though his administration has expanded pre-k funding, “we still have a ways to go.” He estimated “realistically” there would be three or four more years to get to universal pre-k across the state.
“We’d love the federal government to come in and help us fund it but either way we’ll get there,” Murphy said.
The governor took photos with the moms.
Clearview Regional High School senior Ty Whalen seemed almost unbeatable coming into Saturday’s NJSIAA/Rothman Orthopaedics 144-pound State Wrestling final.A defending state champion, Whalen won his first four matches in this tournament by technical fall, out-scoring the opposition, 65-2, but Boonton’s Joe Fongaro had other ideas.The third-seeded Fongaro - a four-time state qualifier who placed sixth last year - took Whalen down in all three periods and notched a 10-9 upset over the No. 1 seed.“When you...
Clearview Regional High School senior Ty Whalen seemed almost unbeatable coming into Saturday’s NJSIAA/Rothman Orthopaedics 144-pound State Wrestling final.
A defending state champion, Whalen won his first four matches in this tournament by technical fall, out-scoring the opposition, 65-2, but Boonton’s Joe Fongaro had other ideas.
The third-seeded Fongaro - a four-time state qualifier who placed sixth last year - took Whalen down in all three periods and notched a 10-9 upset over the No. 1 seed.
“When your foot’s on the line, none of that matters,” said Fongaro of his opponent’s credentials. “You don’t even have to know who the guy is. Pretend you’re wrestling a guy you hate, a teacher you don’t like. Just pound him. I wasn’t wrestling Ty Whalen, I was wrestling myself.”
Fongaro joined his sister, Julia, as a state finalist after she reached a girls state final two weeks ago. He also became the program’s first state champion in 30 years.
“There’s nothing like being a Bomber,” said Fongaro. “I have the best coaches. A lot of people say that, but I really mean it.”
Fongaro used takedowns in the first and second periods to build a 6-4 lead going into the third. He nearly put Whalen on his back in the second period, but the Pioneer senior was able to make it to his stomach.
Whalen almost won the match on top as a tilt to start the third period tied it up before a Fongaro reversal made it 8-6.
Whalen escaped and went for a throw, and Fongaro countered on the line for his own takedown and 10-7 lead. The Pioneer standout closed the gap with an escape and stall point, but Fongaro held him off the final seconds to record the upset and win his first state title.
“I thought winning in the semis was the greatest feeling, this is better,” said an emotional Fongaro. “This is everything I worked for, all the extra work after practice. Every single rep led to this. It all started watching my brother (Danny) try to achieve this and this was my final chance, I wasn’t going to let it slip.”
Whalen was trying to become the first two-time state champion in program history after winning as a junior last year. He was a three-time region and district champ and also has a fourth-place finish in the state to his credit.
Saturday’s final was a matchup we could see in the future with Whalen bound for Princeton and Fongaro for Rutgers.
“He’s a great opponent,” said Fongaro. “I like wrestling great opponents. I look forward to wrestling him in the future. I know I will.”
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For years, the onset of winter weather meant an end to the restoration of the dozens of trains parked at Boonton's United Railroad Historical Society of New Jersey rail yard. At least until the crocuses returned.Now, through rain, snow or gloom of night, you can find members of the group and its sister group, Tri-State Railway Historical Society, welding and repairing a conga line of railcars and engines in dire need of some TLC."This is a real game changer for us," Richie King, Tri-State's president, s...
For years, the onset of winter weather meant an end to the restoration of the dozens of trains parked at Boonton's United Railroad Historical Society of New Jersey rail yard. At least until the crocuses returned.
Now, through rain, snow or gloom of night, you can find members of the group and its sister group, Tri-State Railway Historical Society, welding and repairing a conga line of railcars and engines in dire need of some TLC.
"This is a real game changer for us," Richie King, Tri-State's president, said of the 6,600-square-foot building that is the first indoor workspace URHS has owned in its 37-year history.
“For more than a decade, we had been working out of an old boxcar. This upgrade could not be a bigger deal for our volunteers,” said URHS President Kevin Phalon.
The 66-by-100-foot building is constructed primarily out of recycled shipping containers. It provides for two passenger-car-lengths of workspace under cover, plus 3,200 square feet of indoor storage and workspace in the containers themselves.
Built in 2012, the building was previously leased to a for-profit entity until that lease ended in October.
The United Railroad Historical Society took that opportunity to move its own operations into the building, and it is looking to raise $25,000 to get the workspace up to snuff. Individuals can donate directly to URHS online at URHS.org/donate, or by mail to 104 Morris Ave., Boonton NJ 07005.
“We still have a long way to go to turn this building into a full-fledged restoration shop,” Phalon said.
Volunteers intend to outfit each of the four ground-floor containers into shops for tools, welding and machines, paint and body, and parts storage.
“Now that we have an indoor space, we are able to do work that we could never do before,” said lead mechanic Erik Stenzel. “We are looking to acquire more shop machinery such as lathes, a milling machine and other metalworking tools to outfit our soon-to-be machine shop.”
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In all, there are roughly 60 engines and rail cars at the yard, including the New York Central Hickory Creek and Tavern-Lounge No. 43. The former was once the premier car of the 20th Century Limited train. It was inaugurated in 1948 by then-Gen. Dwight Eisenhower and offered luxury service between New York and Chicago.
The Hickory Creek car is used for a key fundraiser for the group, which runs excursions between Manhattan and Albany in the fall.
Last year, "The $300 tickets sold out in a few minutes," King said.
The groups' plan is first to promote the operations via events to show off the working cars and engines to the public at their new digs. Ultimately the plan is to foster a movement to create a museum to pay proper homage to New Jersey's role in railroad history.
Too many don't realize that New Jersey was the birthplace of locomotives and railroads, Phalon said.
It began with John Stevens' patenting of a practical steam engine shortly after the country's founding.
Then. in 1812, Stevens, a Revolutionary War veteran and colonel, published a pamphlet titled "Documents Tending to Prove the Superior Advantages of Rail-Ways and Steam-Carriages over Canal Navigation."
To prove trains' feasibility, Stevens built the first American steam locomotive on a 0.5-mile (0.8-kilometer) circular track on his Hoboken estate.
In 1815 the New Jersey Legislature granted Stevens the country's first charter for a railroad. This led to the formation in 1830 of the Camden & Amboy Railroad and Transportation Co.
One day, the goal for the historical groups is to prepare cars for display and use for a New Jersey Rail Museum.
Matt Fagan is a local reporter for NorthJersey.com. For unlimited access to the most important news from your local community, please subscribe or activate your digital account today.
What better way to show off extensive renovations at the historic Boonton Holmes Library than to have it host the town's first-ever book festival?With many interior and exterior improvements completed, the nonprofit Boonton Main Street organization conducted a groundbreaking Friday for a new backyard courtyard that will include a stage for intimate outdoor performances and events.The Boonton Books and Beyond Festival will welcome more than 30 authors and presenters at the library, the Boonton Coffee Company and t...
What better way to show off extensive renovations at the historic Boonton Holmes Library than to have it host the town's first-ever book festival?
With many interior and exterior improvements completed, the nonprofit Boonton Main Street organization conducted a groundbreaking Friday for a new backyard courtyard that will include a stage for intimate outdoor performances and events.
The Boonton Books and Beyond Festival will welcome more than 30 authors and presenters at the library, the Boonton Coffee Company and the Boonton Elks Lodge from 10 a.m. to 5 p.m. on Nov. 13.
With support from Boonton Mayor Richard Corcoran, the event was conceived "as a celebration of New Jersey’s own homegrown artists and authors, whether hailing from or based in the Garden State."
“We are delighted with the overwhelmingly positive response from so many of the state’s outstanding writers,” said Tracy Pryer, Boonton’s director of recreation and festival co-chair. “The events will all be in-person, with appropriate COVID precautions in place, of course. So it’s a great opportunity for book lovers to meet and interact with authors.”
The participants represent a wide range of genres, including literary fiction, mystery, children’s picture books, TV scripts, comic books and more.
The festival presents a homecoming opportunity for Boonton Township native Gina Ippolito, who recently completed a two-year run as a scriptwriter for the CBS sitcom "The Unicorn."
"I think it's very cool that Boonton and Boonton Township and the surrounding areas have produced so many prolific writers with varied resumes," said Ippolito, who also wrote for the "Murphy Brown" reboot. "I'm excited to hear all of them speak. I think the whole town should be, too."
Ippolito recalls spending time at the Holmes Library as a child when her mother would study there for a graduate degree.
"She would just park me in the kids' section and I would devour the books until we left," Ippolito said. "It was one of my favorite places. I still have some of the free bookmarks they gave out."
Also appearing will be former Daily Record journalist Lorraina Ash, editor of the award-winning book "Corona City: One Anthology’s Remarkable Journey." Four contributing writers will join her for a discussion about the book, which compiled first-person stories and photography that follows life during the first months of the COVID-19 pandemic in the New York-New Jersey region.
Festival events are free. Signed books from the presenters will be available for purchase.
“The festival schedule features more than 25 presentations in separate venues throughout the day,” library Director Lotte Newlin said. “That way, there will be something for all interests at any given time. Audiences should definitely plan to make a day of attending.”
Steven Kampschmidt, president of Boonton Main Street, said he hopes the festival will bring patronage to restaurants in town, some of which will feature a special prix-fixe lunch menu for the day.
“It’s great to have the participation of our fine eating establishments," he said. "It’s another excellent reason to visit Boonton on November 13.”
Presenters and visitors will find extensive renovations have already been completed at the library, including a bright new blue exterior color chosen to be appropriate for the Victorian Era, when the library was established at the top of Main Street and the corner of Boonton Avenue.
James Holmes donated the former residence in 1870 to be used as a library. The library received a makeover in 2010 after it was deeded over to the town.
More recently, a grant of $221,360 in 2020 from the Morris County Historic Preservation Trust Fund helped fund partial exterior restoration of the south, east and west elevations, including repairs to the siding and trim, restoration of wood windows, and painting.
Visit the festival website at www.boontonbooks.org for more information.
William Westhoven is a local reporter for DailyRecord.com. For unlimited access to the most important news from your local community, please subscribe or activate your digital account today.