The most common reason for menopause is the natural decline in a female's reproductive hormones. However, menopause can also result from the following situations:
Oophorectomy: This surgery, which removes a woman's ovaries, causes immediate menopause. Symptoms and signs of menopause in this situation can be severe, as the hormonal changes happen abruptly.
Chemotherapy: Cancer treatments like chemotherapy can induce menopause quickly, causing symptoms to appear shortly after or even during treatment.
Ovarian Insufficiency: Also called premature ovarian failure, this condition is essentially premature menopause. It happens when a woman's ovaries quit functioning before the age of 40 and can stem from genetic factors and disease. Only 1% of women suffer from premature menopause, but HRT can help protect the heart, brain, and bones.
If you're a woman going through menopause and find that you have become increasingly depressed, you're not alone. It's estimated that 15% of women experience depression to some degree while going through menopause. What many women don't know is that depression can start during perimenopause, or the years leading up to menopause.
Depression can be hard to diagnose, especially during perimenopause and menopause. However, if you notice the following signs, it might be time to speak with a physician:
Remember, if you're experiencing depression, you're not weak or broken - you're going through a very regular emotional experience. The good news is that with proper treatment from your doctor, depression isn't a death sentence. And with HRT and anti-aging treatment for women, depression could be the catalyst you need to enjoy a new lease on life.
Hot flashes - they're one of the most well-known symptoms of menopause. Hot flashes are intense, sudden feelings of heat across a woman's upper body. Some last second, while others last minutes, making them incredibly inconvenient and uncomfortable for most women.
Symptoms of hot flashes include:
Typically, hot flashes are caused by a lack of estrogen. Low estrogen levels negatively affect a woman's hypothalamus, the part of the brain that controls body temperature and appetite. Low estrogen levels cause the hypothalamus to incorrectly assume the body is too hot, dilating blood vessels to increase blood flow. Luckily, most women don't have to settle for the uncomfortable feelings that hot flashes cause. HRT treatments for women often stabilize hormones, lessening the effects of hot flashes and menopause in general.
Mood swings are common occurrences for most people - quick shifts from happy to angry and back again, triggered by a specific event. And while many people experience mood swings, they are particularly common for women going through menopause. That's because, during menopause, the female's hormones are often imbalanced. Hormone imbalances and mood swings go hand-in-hand, resulting in frequent mood changes and even symptoms like insomnia.
The rate of production of estrogen, a hormone that fluctuates during menopause, largely determines the rate of production the hormone serotonin, which regulates mood, causing mood swings.
Luckily, HRT and anti-aging treatments in Watchung, NJ for women work wonders for mood swings by regulating hormone levels like estrogen. With normal hormone levels, women around the world are now learning that they don't have to settle for mood swings during menopause.
Staying fit and healthy is hard for anyone living in modern America. However, for women with hormone imbalances during perimenopause or menopause, weight gain is even more serious. Luckily, HRT treatments for women coupled with a physician-led diet can help keep weight in check. But which hormones need to be regulated?
Lowered sexual desire - three words most men and women hate to hear. Unfortunately, for many women in perimenopausal and menopausal states, it's just a reality of life. Thankfully, today, HRT and anti-aging treatments Watchung, NJ can help women maintain a normal, healthy sex drive. But what causes low libido in women, especially as they get older?
The hormones responsible for low libido in women are progesterone, estrogen, and testosterone.
Progesterone production decreases during perimenopause, causing low sex drive in women. Lower progesterone production can also cause chronic fatigue, weight gain, and other symptoms. On the other hand, lower estrogen levels during menopause lead to vaginal dryness and even vaginal atrophy or loss of muscle tension.
Lastly, testosterone plays a role in lowered libido. And while testosterone is often grouped as a male hormone, it contributes to important health and regulatory functionality in women. A woman's testosterone serves to heighten sexual responses and enhances orgasms. When the ovaries are unable to produce sufficient levels of testosterone, it often results in a lowered sex drive.
Often uncomfortable and even painful, vaginal dryness is a serious problem for sexually active women. However, like hair loss in males, vaginal dryness is very common - almost 50% of women suffer from it during menopause.
Getting older is just a part of life, but that doesn't mean you have to settle for the side effects. HRT and anti-aging treatments for women correct vaginal dryness by re-balancing estrogen, progesterone, and testosterone. When supplemented with diet and healthy living, your vagina's secretions are normalized, causing discomfort to recede.
Uterine fibroids - they're perhaps the least-known symptom of menopause and hormone imbalances in women. That's because these growths on the uterus are often symptom-free. Unfortunately, these growths can be cancerous, presenting a danger for women as they age.
Many women will have fibroids at some point. Because they're symptomless, they're usually found during routine doctor exams. Some women only get one or two, while others may have large clusters of fibroids. Because fibroids are usually caused by hormone imbalances, hysterectomies have been used as a solution, forcing women into early menopause.
Advances in HRT and anti-aging medicine for women give females a safer, non-surgical option without having to experience menopause early. At Global Life Rejuvenation, our expert physicians will implement a customized HRT program to stabilize your hormones and reduce the risk of cancerous fibroid growth.
Endometriosis symptoms are much like the effects of PMS, and include pelvic pain, fatigue, cramping, and bloating. While doctors aren't entirely sure what causes this painful, uncomfortable condition, most agree that hormones - particularly xenoestrogens - play a factor.
Endometriosis symptoms are much like the effects of PMS and include pelvic pain, fatigue, cramping, and bloating. While doctors aren't entirely sure what causes this painful, uncomfortable condition, most agree that hormones - particularly xenoestrogens - play a factor.
Xenoestrogen is a hormone that is very similar to estrogen. Too much xenoestrogen is thought to stimulate endometrial tissue growth. HRT for women helps balance these hormones and, when used with a custom nutrition program, can provide relief for women across the U.S.
Sermorelin is a synthetic hormone peptide, like GHRH, which triggers the release of growth hormones. When used under the care of a qualified physician, Sermorelin can help you lose weight, increase your energy levels, and help you feel much younger.
Human growth hormone (HGH) therapy has been used for years to treat hormone deficiencies. Unlike HGH, which directly replaces declining human growth hormone levels, Sermorelin addresses the underlying cause of decreased HGH, stimulating the pituitary gland naturally. This approach keeps the mechanisms of growth hormone production active.
Ipamorelin helps to release growth hormones in a person's body by mimicking a peptide called ghrelin. Ghrelin is one of three hormones which work together to regulate the growth hormone levels released by the pituitary gland. Because Ipamorelin stimulates the body to produce growth hormone, your body won't stop its natural growth hormone production, which occurs with synthetic HGH.
Ipamorelin causes growth hormone secretion that resembles natural release patterns rather than being constantly elevated from HGH. Because ipamorelin stimulates the natural production of growth hormone, our patients can use this treatment long-term with fewer health risks.
One of the biggest benefits of Ipamorelin is that it provides significant short and long-term benefits in age management therapies. Ipamorelin can boost a patient's overall health, wellbeing, and outlook on life.
When there is an increased concentration of growth hormone by the pituitary gland, there are positive benefits to the body. Some benefits include:
Whether you are considering our HRT and anti-aging treatments for women in Watchung, NJ, we are here to help. The first step to reclaiming your life begins by contacting Global Life Rejuvenation. Our friendly, knowledgeable HRT experts can help answer your questions and walk you through our procedures. From there, we'll figure out which treatments are right for you. Before you know it, you'll be well on your way to looking and feeling better than you have in years!973-587-8638
Donna Gelegonya has been talking about retiring from teaching and coaching swimming at Morristown High School for several years. But the timing was never quite right.Gelegonya had hoped her longtime assistant, Bobby Sparano, would take over. But he has a young family, as does assistant Bernadette Componile.Gelegonya refused to be forced out by COVID. But in the summer of 2021, Sparano became the Morris School District's assistant director of human resources − an administrative position that would keep him o...
Donna Gelegonya has been talking about retiring from teaching and coaching swimming at Morristown High School for several years. But the timing was never quite right.
Gelegonya had hoped her longtime assistant, Bobby Sparano, would take over. But he has a young family, as does assistant Bernadette Componile.
Gelegonya refused to be forced out by COVID. But in the summer of 2021, Sparano became the Morris School District's assistant director of human resources − an administrative position that would keep him off the pool deck.
Gelegonya wasn't quite out of options. She reached out to Joe Cecala, a former three-sport athlete at Morristown who had revitalized the Bayonne High School swim program.
Cecala, 32, achieved "my dream and goal since I was a young kid" while ensuring the smooth transition Gelegonya hoped for. He is a physical education and health teacher responsible for teaching swimming classes and managing the Morristown High School pool.
A lifelong swimmer, Cecala also played fullback, linebacker, kicker and punter on the Colonials football team. He was a bullpen catcher on the baseball team's NJSIAA Group 3 title in 2006. He was a substitute teacher and volunteer assistant in all three sports after graduating from Springfield College in 2012, then got a full-time teaching and swim coaching job at Bayonne.
When Cecala arrived as an assistant six years ago, there were 18 swimmers on the team. That had ballooned to 60 in his first year as head coach, and he had to start making cuts a season later. The Bayonne girls won the Hudson County Interscholastic Athletic League title in 2016, after a rare two-year absence from the top.
With few club swimmers, Cecala had to do stroke instruction and other hands-on coaching which will be more rare at Morristown. He also predicted he'll be one of the loudest coaches, and likely more stern than Gelegonya.
"It's exciting to be back where it all started, full circle," said Cecala, who lives in his Morris Plains hometown with his wife, Kate, and their two young children, Evelyn and Joseph.
"I'd like to think I'm more proficient with the knowledge behind swimming. I love the sport. It's always been a dream of mine to come back."
Joe Cecala isn't the most heralded swim coach in his own family.
That honor goes to his mother, Tina Cecala, who led the Morris Plains summer swim program for 34 years − including eight with her kids, Corrine and Joe, at her side. Tina Cecala taught physical education at Watchung Hills for 33 years, retiring in 2012, and also coached the girls swim team (140-21-2) to five NJSIAA Public B titles and eight Somerset County titles. She has been inducted into the Watchung Hills High School and the New Jersey Interscholastic Coaches Association Halls of Fame.
Corinne Cecala coached varsity field hockey and JV softball at North Plainfield.
"I told them on Day One, 'I want you to make your name yourself with me. I don't care about the past. I don't care what has or hasn't happened. I want you to show me who you are and what you can do,'" said Cecala, a physical education teacher who will also run Morristown's pool, home to multiple local high school teams.
"To get to that next level of fast is exciting, to have a (Meet of Champions) berth, and try to make a run deep into the season. I plan to keep Morristown as a true swimming school, and really build back the family aspect of the team − as well as trying to compete for a state title."
Gelegonya had a 320-96-6 record with the Morristown girls, including four division titles, two Morris County championships, and seven sectional trophies. The Colonials boys went 264-157-4 under Gelegonya, including six Morris County and three sectional titles.
Gelegonya was named a girls swimming Northeast Sectional Coach of the Year by the National Federation of State High School Associations in 2009. She was inducted into the New Jersey State Coaches Association Hall of Fame in 2017.
Gelegonya is still waking up early, but the 4:30 a.m. alarms and long drives from Hunterdon County to Morristown are quickly becoming an unpleasant memory. She's been "trying to clear 30 years of clutter" from her family's home. She hopes to travel with her husband, Ron, and spend more time with their blended family.
"You have to start new adventures," she said. "I do miss the kids. The biggest thing I'm having trouble with is control. I'm so used to being in control of the pool and what happens there. Giving it all up cold turkey, it's different for me. Even though it's difficult, I know I left it to somebody who can handle it."
Somerset County Sheriff’s Office to Collect Toys for Tots Donate a Toy by Dec. 13 to Bring a Child Joy This HolidaySOMERVILLE, NJ - Local resident Somerset County Sheriff Darrin J. Russo and the Marine Toys for Tots Foundation is encouraging the community to donate to the 2022 Toys for Tots collection drive this holiday season.“Every child deserves a Christmas. The holidays can be one of the most trying times for families who feel they cannot give their children what they need,” said Sheriff R...
Somerset County Sheriff’s Office to Collect Toys for Tots Donate a Toy by Dec. 13 to Bring a Child Joy This Holiday
SOMERVILLE, NJ - Local resident Somerset County Sheriff Darrin J. Russo and the Marine Toys for Tots Foundation is encouraging the community to donate to the 2022 Toys for Tots collection drive this holiday season.
“Every child deserves a Christmas. The holidays can be one of the most trying times for families who feel they cannot give their children what they need,” said Sheriff Russo. “During these difficult economic times, let’s help put a smile on the face of every child by donating an unwrapped, new toy.”
Donated toys must be new and unwrapped, safe (non-choking hazard toys for infants and toddlers), and age-appropriate (newborn to 14) for both boys and girls (newborn to 14). Toy gun replicas and gift cards will NOT be accepted.
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Local residents can drop off toys at the Park Ranger Station on 156 Mettlers Road in Colonial Park until Tuesday Dec. 13.
“We hope the generosity from our employees and residents continues this year to support this great cause,” said Sergeant Joseph Bialiy. “Many thanks to those who contributed last year.”
The Sheriff’s Office has partnered with the Somerset County Park Commission to offer five over locations:
For more information about donating to Toys for Tots at the Somerset County Park Commission, call Somerset County Park Commission Administrator of Leisure and Community Services Dina Trunzo, CTRS at 908-722-1200 ext. 5234. For hours of operation, visit www.somersetcountyparks.org
Marine Toys for Tots Foundation The mission of the Marine Toys for Tots Foundation is to assist the U. S. Marine Corps in providing a tangible sign of hope to children in-need at Christmas. This assistance includes providing day-to-day leadership and oversight of the Program, raising funds to provide toys to supplement the collections of local Toys for Tots Campaigns, providing promotional support, and defraying the costs of conducting annual Toys for Tots Campaigns.
Acquisition accelerates Full-Life's transformation into clinical stage radiopharmaceutical company, leveraging its European-focused Radiotechnology and Development Platform BRUSSELS and WATCHUNG, N.J. and SHANGHAI, Nov. 28, 2022 /PRNewswire/ -- Full-Life Technologies, a fully integrated global radiotherapeutics company, today announced an agreement to acquire New Jersey-based Focus-X Therapeutics, a company developing targeted radiopharmaceuticals to treat cancer based on proprietary peptide engineering technology. The acquisit...
Acquisition accelerates Full-Life's transformation into clinical stage radiopharmaceutical company, leveraging its European-focused Radiotechnology and Development Platform
BRUSSELS and WATCHUNG, N.J. and SHANGHAI, Nov. 28, 2022 /PRNewswire/ -- Full-Life Technologies, a fully integrated global radiotherapeutics company, today announced an agreement to acquire New Jersey-based Focus-X Therapeutics, a company developing targeted radiopharmaceuticals to treat cancer based on proprietary peptide engineering technology. The acquisition expands Full-Life's pipeline, including two compounds nearing clinical trials, provides a second innovative peptide focused discovery platform, and leverages its Radio Technology manufacturing and logistics platforms to advance compounds into clinical development.
Under the terms of the acquisition, Focus-X shareholders are eligible to receive from Full-Life an upfront payment, potential development, regulatory and sales-based milestones of up to $245 million and royalties on any commercial sales. The acquisition is expected to close in the first quarter of 2023.
"The Focus-X acquisition perfectly leverages Full-Life's radiotechnology and development platform by adding two development ready compounds, including a lead with initial human data, a robust pipeline and world class peptide discovery capabilities," said Lanny Sun, Co-founder, Chairman and CEO of Full-Life.
Fa Liu, PhD, Focus-X's Co-founder and CEO commented, "Full-Life's integrated platforms will provide the manufacturing technology, logistics and clinical development expertise to accelerate development of our compounds as well as expand our discovery efforts. This world class radiopharmaceutical team has enormous potential to develop radiopharmaceutical therapeutics that impact patients worldwide."
Founded in 2020, Focus-X has developed a proprietary engineering platform to develop peptide radioligands that precisely deliver alpha or beta emitters to breakdown cancer cell DNA. The platform enables high-quality optimization of peptide radioligand vectors for key pharmaceutical attributes such as biodistribution, binding affinity and in vivo stability. Such optimization can present significant challenges to other ligand targeting compounds such as antibodies. The company has focused on both validated targets and new mechanisms.
Focus-X has established a substantial pipeline. The company's two lead compounds in development are a prostate specific membrane antigen (PMSA)-targeted peptide for the treatment of metastatic castration resistant prostate cancer and a neurotensin receptor type 1 (NTSR1)-targeted peptide for the treatment of pancreatic cancer. The PMSA-targeted compound is currently undergoing an investigator-initiated imaging study. Focus-X has six other programs in earlier stages of development.
About Full-Life Technologies
Full-Life Technologies Limited ("Full-Life") is a fully integrated global radiopharmaceutical company with operations in Europe and China. We seek to own the entire value chain for radiopharmaceutical research & development, production & commercialization in order to deliver clinical impact for patients. The company plans to attack core issues affecting radiopharmaceuticals today through innovative research that targets the treatments of tomorrow. We are comprised of a team of fast-moving entrepreneurs and scientists with a demonstrated track record in the life sciences, as well as radioisotope research and clinical development.
SOURCE Full-Life Technologies Limited
The Historic Preservation Commission received praise and money for its efforts to preserve historic buildings in Westfield.WESTFIELD, NJ — Westfield's Historic Preservation Commission, a group that is dedicated to preserving and protecting historical assets in the town, was recently recognized for its efforts by the state of the New Jersey.Preservation New Jersey, a nonprofit group that promotes the economic vitality, sustainability and heritage of New Jersey's diverse communities, presented the HPC with a Historic Pres...
WESTFIELD, NJ — Westfield's Historic Preservation Commission, a group that is dedicated to preserving and protecting historical assets in the town, was recently recognized for its efforts by the state of the New Jersey.
Preservation New Jersey, a nonprofit group that promotes the economic vitality, sustainability and heritage of New Jersey's diverse communities, presented the HPC with a Historic Preservation Commission Award. In addition, the HPC received a total of $60,000 in grants from both the state and the town of Westfield.
The preservation award recognizes organizations and individuals that have made important and sustained contributions to the understanding and promotion of historic preservation and history in New Jersey, according to Mayor Shelley Brindle.
Preservation NJ cited the HPC's engagement of local citizens regarding the need for, and benefits of, local historic preservation.
In addition, HPC was awarded a $45,000 grant by The New Jersey Historic Trust — an affiliate of the New Jersey Department of Community Affairs whose mission is to save and promote historic sites throughout the state.
Westfield was one of 27 grant recipients awarded funds to support preservation planning projects, according to Mayor Brindle.
The town also provided a $15,000 match to the HPC. Maria Boyes, the chair of the HPC, said the group will use this grant money to identify and secure designations for potential landmarks.
In the past five years, there have been nine voluntary designations of historic properties, Brindle wrote on Facebook.
Brindle thanked the HPC for their hard work and dedication at last week's council meeting.
"What I love most about what has transpired is that we have let it be known in this community that we value historic preservation," Brindle said. "People are not going to voluntarily designate their homes if they don't think it's something that their community values. When you put a stake in the ground and say this is important, and this is who we are, people are more inclined to want to be a part of that."
In September of 2020, the council passed a controversial revision of the town's preservation ordinance in order to prevent historic buildings from being torn down.
Proponents believed it would protect the town's many historic homes from losing their character or from being demolished. But opponents felt the ordinance ties owners' hands when they want to make changes to their property.
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WATCHUNG – Picturesque Best Lake is considered one of the borough’s aesthetic jewels but apparently a problem lurks beneath the surface.Green sunfish, considered an invasive species in New Jersey and several other states, exist in sufficient enough numbers in Best Lake to pose a peril to bass that also live there.The threat to large mouth bass is serious enough that it may dissuade the state Department of Environmental Protection (DEP) from restocking the lake in the future, according to Borough Cou...
WATCHUNG – Picturesque Best Lake is considered one of the borough’s aesthetic jewels but apparently a problem lurks beneath the surface.
Green sunfish, considered an invasive species in New Jersey and several other states, exist in sufficient enough numbers in Best Lake to pose a peril to bass that also live there.
The threat to large mouth bass is serious enough that it may dissuade the state Department of Environmental Protection (DEP) from restocking the lake in the future, according to Borough Councilwoman Wendy Robinson.
Robinson, who is liaison to the Environmental Commission, said that group discussed the situation at its October meeting. Doug Speeney a commission member who is a DEP environmental specialist, became aware of the green sunfish issue through his contacts at the state agency.
The Borough Council got a brief rundown on the problem from Robinson at its Nov. 3 meeting.
The DEP has yet to officially say it will not restock Best Lake in the future, but the commission anticipates needing to take some type of action to address the situation, Robinson said. Consultations with the state agency will likely be included, she added.
The state encourages anglers to destroy green sunfish if caught while fishing. Best Lake, however, has posted signs stating the municipal policy is catch and release while fishing.
Robinson said the commission may ask the council to change that policy for green sunfish, encouraging anglers to instead dispose of them in some way. That would require a public education campaign, she said.
Logistical issues would also need to be resolved. Robinson said there is no desire to have the fish disposed of at Best Lake, where doing so in large numbers would create an odor problem.
So far, there is no indication that a similar green sunfish problem exists as nearby Watchung Lake, said Robinson.
Their aggressive nature toward food sources make green sunfish a threat to other species. They prefer live food and slow-moving bodies of water and are adaptable.
Sunfish green sunfish consume a wide variety of prey and feed on the young of other fish species. They can quickly grow in numbers, limiting the growth of other species.
“Green sunfish have a larger mouth than the state’s native sunfish, thus have the ability to outcompete native fish,” according to the New Jersey Division of Fish and Wildlife website.
Their growing dominance at Best Lake came to the attention of the DEP several years ago, Robinson said, when the agency seined the waterway as it does periodically. Seining involves catching fish in a large net. When the DEP did so at Best Lake, there were few large mouth bass in the catch.
Robinson said there is no way to conclusively pinpoint how green sunfish made their way to Best Lake, but migration is one a possibility. “It’s a regional problem,” she said. “You can’t say someone just brought them there and they started multiplying.”